Voriconazole therapeutic drug monitoring.

نویسندگان

  • J Smith
  • N Safdar
  • V Knasinski
  • W Simmons
  • S M Bhavnani
  • P G Ambrose
  • D Andes
چکیده

We report on 28 patients who underwent voriconazole monitoring because of disease progression or toxicity. A relationship (P<0.025) between disease progression and drug concentration was detected. Favorable responses were observed in 10/10 patients with concentrations above 2.05 microg/ml, while disease progressed in 44% (n=18) of patients with concentrations below 2.05 microg/ml.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 50 4  شماره 

صفحات  -

تاریخ انتشار 2006